It is most common in young children who have not been fully vaccinated and in. This study demonstrates several anatomic and technical factors that can affect the neural response to SCS. This is an infection of the lining of your airways. Changing the dura conductivity also produced significant differences in activation thresholds. Variability in electrode impedance produced significant changes in activation thresholds for voltage-controlled stimulation (38% to 51%), but had little effect on activation thresholds for current-controlled stimulation (less than 13%). Rostrocaudal positioning of the cathode with respect to the vertebrae had a large effect (up to 32%) on activation thresholds. Several anatomic and modeling factors produced significant percent differences or errors in activation thresholds. dura conductivity, frequency-dependent conductivity). current-controlled), electrode impedance, lead position, lead type, and electrical properties of surrounding tissues (e.g. spine geometry, dorsal rootlet anatomy), stimulation type (i.e. We then investigated how activation thresholds changed as a function of several anatomical variables (e.g. We positioned multicompartment models of sensory axons within the spinal cord to calculate the activation threshold for each sensory axon. We developed computational models that consisted of detailed finite element models of the lower thoracic spinal cord, surrounding tissues, and implanted SCS electrode arrays. Therefore, the goal of this study was to investigate several anatomic and technical factors that may affect model-based predictions of neural activation during thoracic SCS. However, it is imperative that these computational models include the appropriate level of detail to accurately predict the neural response to SCS and to correlate model predictions with clinical outcomes. Computational models represent a valuable tool to study the potential mechanisms of action of SCS and to optimize the design and implementation of SCS technologies.

Spinal cord stimulation (SCS) is a common neurostimulation therapy to treat chronic pain.

Dorsal column stimulator cough